Derma 2.0 Active Ingredients ✨
Understanding the science behind the skin-transforming actives
The power of aesthetic medicine lies in its ingredients. Each molecule in a formulation plays a unique role in rejuvenating, repairing, or protecting the skin.
Choosing the right ingredients is just the beginning — the true power of Derma 2.0 lies in the meticulous sourcing of medical-grade actives and the rigorous third-party testing not only of each ingredient, but how they interact together within formulations under varying temperatures, application methods, and over time. This is where science meets skincare excellence.
In the Derma 2.0 mesotherapy/microneedling system, over 40 clinically proven actives work in harmony to deliver visible, lasting results. Here’s your go-to breakdown of what they are, how they work, and why they’re used in Derma 2.0’s advanced skin and body care treatments.
🧬 Amino Acids
Vital building blocks for proteins like collagen and elastin. They support tissue repair, improve hydration, and increase skin resilience. In hair treatments, amino acids boost follicle strength and growth.
🧖♀️ Acetyl Decapeptide-3
A biomimetic peptide known for skin regeneration and elasticity. It promotes cell communication and stimulates the production of essential extracellular matrix proteins.
💉 Acetyl Hexapeptide-30
A powerful peptide that mimics Botox-like activity. It helps reduce muscle contraction and softens dynamic wrinkles, making it a staple in anti-aging therapies.
🌿 Azelamidopropyl Dimethyl Amine
A gentle seboregulator with antimicrobial and anti-inflammatory properties. It targets acne and oily skin conditions without causing dryness or irritation.
🌟 Azeloglicina
A molecule combining azelaic acid and glycine. It regulates sebum production, brightens the skin, and has anti-inflammatory benefits, ideal for acne and rosacea.
🔒 Argireline (Acetyl Hexapeptide-8)
A topical alternative to injectables, it relaxes facial tension and reduces the appearance of expression lines. It’s safe, effective, and widely used in wrinkle prevention.
🥬 Artichoke Extract
Rich in antioxidants and flavonoids, it promotes lymphatic drainage and improves skin texture. It’s also used to reduce puffiness and stimulate microcirculation.
🌼 Arbutin
A skin-brightening agent derived from plants, it inhibits tyrosinase to reduce melanin production. Perfect for treating hyperpigmentation and melasma.
🌸 Bisabolol
A soothing agent found in chamomile. It calms irritation, promotes healing, and enhances the penetration of other active ingredients.
💇♀️ Biotin (Vitamin B7)
Essential for healthy skin and hair. Biotin improves keratin structure, combats hair thinning, and supports a strong skin barrier.
☕ Caffeine
Well-known for its decongesting and lipolytic properties. It reduces under-eye puffiness and is often used in cellulite and fat-dissolving formulas.
🔥 Carnitine
Promotes fat metabolism and energy production in cells. In aesthetics, it supports fat breakdown and stimulates hair follicle vitality in scalp treatments.
🌿 Centella Asiatica Extract
Also known as Gotu Kola, it is revered for its wound-healing and anti-inflammatory properties. It stimulates collagen synthesis and repairs skin damage.
🍄 Cordyceps Sinensis & Trametes Versicolor Extracts
Medicinal mushrooms with powerful antioxidant and adaptogenic properties. They strengthen the skin barrier, reduce inflammation, and balance the microbiome.
💧 D-Panthenol (Provitamin B5)
An ultra-hydrating ingredient that improves skin elasticity, reduces transepidermal water loss, and promotes healing of wounds and scars.
🧪 Deoxycholic Acid
A bile acid that breaks down fat cell membranes. It is used in mesotherapy to target localised fat deposits in the chin and body.
📈 DMAE (Dimethylaminoethanol)
Provides an instant lifting effect by tightening skin and improving muscle tone. It also has antioxidant benefits and reduces age-related pigmentation.
🌿 Eucalyptus Extract
An antimicrobial and anti-inflammatory botanical extract. It soothes the scalp and skin, enhances circulation, and supports hair health.
🌰 Escin
Derived from horse chestnut, escin boosts capillary strength and reduces swelling. Commonly used in under-eye and anti-cellulite treatments.
💎 Glutathione
A master antioxidant that detoxifies the skin, brightens the complexion, and reduces pigmentation. It also enhances other ingredients’ effects.
💦 Hyaluronic Acid
A superstar hydrator that retains up to 1000x its weight in water. Improves skin plumpness, texture, and overall resilience. Present in varying concentrations for different treatment intensities.
💜 Lavender Extract
Known for its calming and antiseptic properties. It soothes reactive skin and helps restore skin balance after procedures.
🎯 Leuphasyl (Pentapeptide-18)
A neuropeptide that works synergistically with Argireline to reduce facial tension and soften wrinkles—great for mature skin.
🌸 Mallow Extract
Rich in mucilage, this extract hydrates and soothes irritated or sensitive skin.
🧴 Niacinamide (Vitamin B3)
A multitasking vitamin that regulates sebum, strengthens the skin barrier, reduces redness, and fades dark spots.
🧪 Organic Silicon
Improves skin elasticity, stimulates fibroblasts, and enhances collagen and elastin synthesis. Often used in firming and anti-aging treatments.
🧬 Peptide Complex / Biomimetic Peptides
Lab-synthesized peptides that mimic natural growth factors. They stimulate collagen, elastin, and cell regeneration for deep skin rejuvenation.
💣 Phosphatidylcholine
A key lipolytic agent used in fat dissolving treatments. It breaks down fat into fatty acids, which are naturally eliminated by the body.
🍍 Pineapple Extract
Contains bromelain, an enzyme that reduces inflammation, breaks down proteins, and promotes skin healing.
🌊 Pseudoalteromonas Extract
A marine peptide that supports wound healing and increases skin regeneration, making it ideal for scar repair.
💫 Rejuline Complex™
A proprietary peptide blend designed to lift, firm, and tone aging skin through deep dermal support and cell renewal.
⚡ Resorcinol
A potent antioxidant and brightening agent used to treat pigmentation and acne. It also has keratolytic (exfoliating) properties.
🌿 Ruscus Extract
Improves microcirculation and reduces swelling, making it a great choice for anti-cellulite and under-eye treatments.
🧴 Sodium Deoxycholate
Enhances fat emulsification, making it more bioavailable for elimination. Often paired with Phosphatidylcholine for body contouring.
📜 Sodium DNA
A regenerative nucleotide that promotes cell repair and boosts fibroblast activity, increasing tissue regeneration.
🍄 Trametes Versicolor Extract
This mushroom extract has strong antioxidant and immune-regulating properties. It helps repair damage and soothe reactive skin.
🧪 Vitamin A (Retinol)
Speeds up cell turnover, fades pigmentation, and stimulates collagen production. One of the most well-researched anti-aging ingredients.
🍊 Vitamin C
A powerful antioxidant that brightens the skin, stimulates collagen, and protects against environmental damage.
💛 Vitamin E
Moisturising and healing, it works synergistically with Vitamin C to protect skin cells and reduce oxidative stress.
🔋 Vitamins B1, B3, B6, B8
Support skin hydration, reduce inflammation, and promote even skin tone. Each B-vitamin plays a role in maintaining skin vitality and balance.
💡 Sh-Oligopeptide-2
A growth factor that enhances skin regeneration, reduces wrinkles, and improves skin texture by stimulating epidermal repair.
Final Thoughts
The Derma 2.0 active ingredients menu is more than a list—it’s a library of skin science, brought together to support skin health at every stage. Whether you’re targeting aging, pigmentation, acne, or hair loss, each ingredient has a specific, evidence-based role in the aesthetics realm.